Lancets come in multiple sizes and brands that often match the glucose meter they are being used with. Usually, the blood glucose meter you are using will have the size of the lancet needed within its instructions to use with the meter. However, if you're unsure, the most standard size is 30 gauge. For those with thicker skin, the smaller number gauge (25-28 gauge) may be more effective as this is a thicker needle and will work better with your skin. On the other hand, if you tend to have thin skin, you may prefer a 32- or 33-gauge lancet, as thinner needles cause less pain. If you are unsure what size to use it is always best to consult with your diabetes care team.